Detection of angiogenesis will help early diagnosis of cancer.

Detection of angiogenesis will help early diagnosis of cancer.

Australian and Chinese scientists are working on an algorithm that will localize and destroy cancer at an early stage, identifying areas with oncological angiogenesis (the growth of new blood vessels). While experiments are being conducted on laboratory mice, research with the participation of people is still far away.

Angiogenesis is a key process in the development of a cancerous tumor, which requires abundant blood supply for growth and metastasis. The software, which is developed in the Australian Scientific and Applied Research Association (CSIRO), will make it possible to distinguish ordinary vessels from those grown by a malignant tumor and, as a result, to diagnose it faster. 
Scientists from CSIRO have teamed up with researchers from the Shanghai Institute of Applied Physics of the Chinese Academy of Sciences to produce three-dimensional high-resolution images of the brain and liver of mice at different stages of cancer development.

Having studied the detailed images, the Australian team of scientists has developed an algorithm that generates an accurate model of the blood supply to the brain, which contains data on the length and shape of blood vessels and their branches. Previous models could only create a simplified “skeleton” of the blood supply system with limited detail and accuracy.

“We have developed robust algorithms that allow for the early detection and quantitative determination of tissue angiogenesis. This could be a big step forward in the diagnosis and treatment of cancer, ”said Dr. Dadong Wang, a leading researcher at CSIRO. – There is a great interest in these studies, but there is a long way to go before this development can be applied to treating people. We really hope for this and are looking for employees and partners to move on to the next stage in the development of this technology. ”

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